Reply to “In-Hospital Mortality Risk of Older Patients With COVID-19 Infection”

We are delighted by the interest in our research by Dr Kawada and we welcome the opportunity to better clarify the results of our recent study on COVID-19 patients aged ≥80 years old.1 In the study, we explored the overlapping effect between clinical covariates and baseline frailty status, in older patients hospitalized for COVID-19. Our results underlined the independent effect of severe frailty on the risk for in-hospital death, as well as male sex, the severity of disease at presentation, and overall comorbidities ≥3.