Nontraditional Risk Factors for Cardiovascular Events in Active Octogenarians

Cardiovascular disease (CVD) is highly prevalent and contributes to disease burden and mortality in older adults.1 The American Heart Association concluded that CVD is the leading cause of death in octogenarians, followed by cancer and Alzheimer’s disease.1 Studies questioned the validity of traditional CVD risk factors to predict CVD-related events in older adults.2,3 Therefore, we explored differences in nontraditional risk factors between octogenarians with vs without cardiovascular events across a 4.5-year follow-up.