Sarcopenia, a gradual loss of muscle mass and function, has been associated with poor health outcomes. Its correlation with another age-related degenerative process, impaired cognition, remains uncertain. This meta-analysis aimed to determine...
Skeletal muscle wasting, also known as sarcopenia, has recently been identified as a serious comorbidity in patients with heart failure (HF). We aimed to assess the impact of sarcopenia on endothelial dysfunction in patients with HF with reduced...
This is the tenth clinical update. It covers chronic kidney disease, dementia, hypotension, polypharmacy, rapid geriatric assessment, and transitional care.
Women live longer than men but spend more of their life with disability.1 This difference may be due to the higher mTOR, the mammalian (mechanistic) target of rapamycin in males compared to females.2 Both testosterone and estradiol increase mTOR,...
Persons with diabetes mellitus have higher rates of cognitive dysfunction compared to non-diabetics.1 Cognitive dysfunction is associated with poor health outcomes and reduced quality of life.2,3 Early identification of cognitive impairment is...
To investigate the association between polypharmacy and medication regimen complexity with time to first hospitalization, number of hospitalizations, and number of hospital days over a 12-month period.
