Improving Proton Pump Inhibitor Deprescribing: Impact of an Educational Intervention in Italian Nursing Homes

Proton pump inhibitors (PPIs) are among the most commonly prescribed medications for nursing home (NH) residents and are often administered without the criteria for appropriate use.1-3 Previous studies found high rates of inappropriate use of PPIs in NHs,2-4 indicating an urgent need to optimize their prescription. The increasing numbers of prescribed medications (despite gastrotoxic drugs), comorbidities, anticoagulants, and corticosteroids were identified as predictors of inappropriate PPI use.