De-Prescribing for Renal Function in Long-Term Care Residents with Chronic Kidney Disease

Polypharmacy is commonly encountered in Long-term Care (LTC) residents and associated with adverse drug events (ADEs) and worsening function. Data from a prior PI project1 resulted in an average deprescribing (DeP) of 1.3 medications per resident encounter. The presence of Chronic Kidney Disease (CKD) calls for attempts at DeP not only to minimize polypharmacy but also to adjust drug dosage for renal function and prevent harm. While CKD is common in older adults, data on DeP in CKD is scarce.