Benefits of Multi-disciplinary Management in a Patient with Mixed Dementia

Vascular and neurodegenerative disorders frequently present as mixed dementia phenotype. The most common type of mixed dementia is Alzheimer’s Dementia (AD) with vascular dementia. Dementia symptoms can develop at an earlier age when AD and vascular pathologies are both present. AD occurs with the accumulation of amyloid beta into fibrillar plaques and hyperphosphorylated tau into paired helical filament neurofibrillary tangles. Beta-amyloid Positron Emission Tomography (β-PET) can help establish AD diagnosis, as amyloid-beta deposition is a central pathophysiological marker of Alzheimer disease.