AMDA Position Statement on Aducanumab

AMDA–The Society for Post-Acute and Long-Term Care Medicine is compelled to comment on the recent approval of the controversial parenteral Alzheimer's dementia (AD) medication, aducanumab. After considering the evidence, we conclude that the aducanumab trials did not adequately demonstrate safety or efficacy. Moreover, aducanumab has only been studied in individuals with mild cognitive impairment or early-stage dementia due to hyperamyloidosis (eg, AD) and has never been tested in a population representative of nursing home residents.