Avoiding Sodium Polystyrene Sulfate (SPS) in Hyperkalemia

Hyperkalemia, defined as a concentration of potassium greater than 5.5 mEq/L in adults, is commonly found on labwork in the subacute nursing facility, often seen in the setting of kidney disease as a result of impaired excretion of potassium in the urine. Treatment is focused upon inducing potassium loss, often through use of loop diuretics such as furosemide. Sodium polystyrene sulfate (SPS) is often used; however, it carries with it significant associated risks and potential complications.