Comment on “Association Between Serum Alkaline Phosphatase Levels and Sarcopenia in US Adults: A Cross-Sectional Study”

We have read with interest the article entitled “Association Between Serum Alkaline Phosphatase Levels and Sarcopenia in US Adults: A Cross-sectional Study.”1 We would like to express our views on some points. First, we note that the study participants are young adults, with mean ages in the subgroups reported as Q1: 37.52 ± 0.51, Q2: 37.77 ± 0.40, Q3: 38.80 ± 0.37, and Q4: 40.93 ± 0.46 years. Participants older than 20 years were included in the study. However, the Asian Working Group for Sarcopenia (AWGS) defines sarcopenia, without reference to comorbidities, as “age-related loss of skeletal muscle mass accompanied by a decline in muscle strength and/or reduced physical performance.”2 The AWGS 2019 consensus retains age cutoff values of either 60 or 65 years.