Assessing the Geriatric Risk: Excessive Weight Loss and Risk of Falls With GLP-1 Receptor Agonists

Obesity in older adults is a risk factor for falls, which in turn is a major cause of injury and injury-related death.1 Although weight loss is recommended for these patients, the rapid weight loss associated with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can cause muscle loss in older adults, further exacerbating functional impairment and falls.2