External Validation of SCORE2-OP for Predicting Cardiovascular Mortality in Frail Geriatric Outpatients

In preventing atherosclerotic cardiovascular diseases (ASCVDs) in frail older people, it is essential to balance estimated cardiovascular disease (CVD) risk with potential treatment benefits and harms. Systematic Coronary Risk Evaluation 2-Older Persons (SCORE2-OP) estimates CVD risk in older people but has not been validated in frail geriatric patients. We evaluated the performance of SCORE2-OP for predicting CVD mortality in this group.